Web Content Viewer
Actions
When to Collect Newborn Screening Specimens

Births at a hospital or a free standing birth centers

The newborn screening specimen shall be collected between 24 hours and 5 days of life (preferably between 24 and 48 hours of age), and before an infant is discharged from the hospital of birth. If the initial specimen is collected before the infant 24 hours old, a repeat specimen must be collected as soon as possible at least 24 hours after birth.

Infants requiring transfusion

If an infant is to receive a transfusion, a newborn screening specimen shall be collected pre-transfusion, even if the infant is not yet 24 hours of age. If the pre-transfusion specimen is collected before the infant is 24 hours of age, a post-transfusion specimen shall be collected as soon as possible, but at least 24 hours after transfusion.  The date and time of the most recent transfusion (prior to specimen collection) must be recorded on the newborn screening card.

If no pre-transfusion specimen was collected (or transfusion occurred in utero), the newborn screening specimen shall be collected between 24 hours and 5 days of life (preferably between 24 and 48 hours of age). The date and time of the most recent transfusion (prior to specimen collection) must be recorded on the newborn screening card.  A post-transfusion specimen should be collected 30 days following the final blood transfusion, OR quantitative Biotinidase, IRT, and GPUT should be obtained 30 days and hemoglobin electrophoresis or HPLC performed 60-90 days following the final blood transfusion.

ECMO
If possible, obtain a newborn screening specimen prior to initiation of ECMO even if infant is less than 24 hours of age. If no pre-ECMO specimen was obtained, collect a specimen between 24 hours and 5 days of life (preferably between 24 and 48 hours of age). Additional screening should be by the recommendation of the attending physician.


Infants transferred to another facility

For an infant who is transferred to another facility, the newborn screening specimen shall be collected by the facility caring for the infant at 24 hours of age. 

If an infant requires a transfusion prior to 24 hours of age, the facility performing the transfusion should assure that a pre-transfusion specimen is collected. The facility caring for the infant 24 hours after the transfusion should collect the post-transfusion specimen.


Birth outside a hospital or a free standing birth center

The attending physician, certified nurse midwife, the certified nurse practitioner, or clinical nurse specialist shall collect the specimen before the child reaches five days of age, but no sooner than twenty-four hours of age. When no physician, certified nurse midwife, certified nurse practitioner or clinical nurse specialist is in attendance, the health commissioner, upon notification of the birth by the local registrar, shall cause a blood specimen to be collected within five business days after being notified of the birth of a child under this paragraph, but no sooner than when the child reaches twenty-four hours of age.