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TB Manual Chapter 11: Lab Services

The diagnosis, management and control of tuberculosis (TB) relies on accurate laboratory tests, as they provide key information to clinicians (for patient care) and public health agencies (for disease control services). TB Manual Chapter 11: Lab Services outlines the available laboratory tests and their turnaround time for results including: Acid-Fast Bacilli (AFB) smear, culture, drug susceptibility, Nucleic Acid Amplification (NAA) assay, identification of Mycobacteria by high performance liquid chromatography (HPLC) or DNA Probe, and genotyping. Directions for specimen collection of sputum at a healthcare facility and at home are provided, as well as collection of gastric aspirates and bronchoscopy or collection of extrapulmonary specimens. This chapter also provides information on specimen shipment.

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