TB Manual Chapter 5: Diagnosis of TB Disease can be used to classify patients with tuberculosis (TB) and latent tuberculosis infection (LTBI) and detect suspect cases of TB. It also provides information on knowing when to report suspect or confirmed cases of TB and diagnose TB disease. For detecting suspected cases of TB, it utilizes signs and symptoms typical of TB, as well as the difference in chest radiograph (x-ray) of immunocompetent patients vs. immunocompromised patients, and those with advanced human immunodeficiency virus (HIV) infection. For diagnosis of TB, the requirement of a complete medical evaluation includes medical history, HIV screening, physical examination, Tuberculin skin test (TST) or interferon gamma release assay (IGRA), chest radiography, and bacteriologic examination. Bacteriologic tests, Acid-Fast Bacilli (AFB) smear, Nucleic Acid Amplification (NAA) assay, culture, and drug susceptibility are all outlined. This chapter includes scenarios for different TB patients and recommended course of action. It also outlines the Ohio policies, state laws and regulations regarding tuberculosis.
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