TB Manual Chapter 6: Treatment of Disease outlines the overall goal for treatment of tuberculosis (TB): to cure the patient and minimize transmission to others. This chapter outlines the basic treatment principles for TB disease. It provides guidance on the appropriate treatment regimens, first-line drugs like Isoniazid (INH), Pyrazinamide (PZA), Ethambutol (EMB), and Rifampin (RIF), dosages, and duration for patients, assessing the patients’ response to treatment and any side effects or adverse reactions. It allows for determination of therapy completion, the need for post-treatment evaluation. The chapter also provides treatment in special situations, such as when a patient has drug-resistant TB or TB–human immunodeficiency virus (HIV) coinfection.
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